Table 3 Clinical markers of inflammation and ascites miR levels in patients with and without spontaneous bacterial peritonitis.

From: MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis

 

Uninfected ascites

SBP

p

Number of specimens

62

10

 

Culture positive

0

4 (40)

 

Detected microorganisms

0

2 × Escherichia coli

 

1 × Enterobacter cloacae

 

1 × Enterococcus faecium

 

C-reactive protein [mg/dL]

17 (11; 32)

104 (60; 174)

<0.001

White blood cell count [G/L]

7.6 (6.2; 10.5)

9.5 (8.5; 13.6)

0.02

Ascites PMN count [/μL]

24 (9; 54)

1237 (552; 3947)

<0.001

MiR-125b [2−ΔCT × 103]

0.16 (0.06; 0.37)

0.11 (0.06; 0.24)

0.59

MiR-155 [2−ΔCT × 103]

0.03 (0.01; 0.05)

0.06 (0.02; 0.4)

0.04

  1. CT: cycle threshold; MELD: model for end-stage liver disease; miR: microRNA; SBP: spontaneous bacterial peritonitis.
  2. Data are given as median (lower; upper interquartile) absolute number (percent). Statistical analysis with Mann-Whitney-U test.