Figure 3: PEITC modulates histone epigenetic regulators in colon cancer cells.

(a,b) Modulation of histone methyl transferases and demethylases (a) or acetyltransferases and deacetylases (b) in SW620 cells after short- or long-term exposure to low-dose PEITC. Differential protein binding to either euchromatin or heterochromatin in SW620 cells after 6 weeks or 72 hr PEITC treatment was calculated by log2(PEITC-6wks/CON) or log2(PEITC-72 hr/CON).