Figure 4: Expression analysis of antisense RNAs possibly involved in known pathways.

(A) Pathway heat map of antisense read counts mapped onto the corresponding sense protein-coding genes as reported in KEGG with assigned ontology terms. (B) Heat map of antisense read counts mapped onto the corresponding sense protein-coding genes (written in parentheses) of the KEGG cytokine cytokine-receptor interaction pathway. Heat maps of all enriched pathways can be downloaded from the external supplement (see Data availability section for SFig. 7). (C) Box plots of the expression levels of IL6 and IL12A as well as their antisense transcripts AC073072.5 and IL12A-AS1, respectively.