Figure 5: Vitamins A and D strongly counteract the transcriptional response of human monocytes to pathogens. | Scientific Reports

Figure 5: Vitamins A and D strongly counteract the transcriptional response of human monocytes to pathogens.

From: Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection

Figure 5

Graphic representation of the expression dynamic of immune-relevant genes (GO:0002376) differentially regulated by both the pathogens and the vitamins. Patterns are divided by the type of correlation observed between the effects of pathogen and vitamin stimulations: counteractive effect (up-regulation by pathogen and down-regulation by vitamin, or vice versa) and synergistic effect (same direction observed in the differential expression induced by pathogen and vitamin stimulations). Pie charts show the proportion of genes depicting counteractive effects (red) and synergistic effects (green).

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