Figure 1: Suppression of colitis by HD-DC transfer is correlated with splenic IL-4 and IL-10 production. | Scientific Reports

Figure 1: Suppression of colitis by HD-DC transfer is correlated with splenic IL-4 and IL-10 production.

From: Suppression of colitis by adoptive transfer of helminth antigen-treated dendritic cells requires interleukin-4 receptor-α signaling

Figure 1

Individual macroscopic disease scores of mice challenged with DNBS, some of which had received 106 HD-DCs i.p. 48 h prior, were plotted alongside their levels of splenic IL-4 (A) IL-10 (B). Splenic IL-4 and IL-10 in recipients of HD-DCs were plotted against each other in (C). Cytokine levels were measured by ELISA from the supernatants of conA (2 μg/mL) stimulated splenocytes (5 × 106/mL). As a D’Agonstino & Pearson omnibus normality test determined cytokine data was not normally distributed; Spearman correlation test was performed for all graphs. Data from 4 independent experiments.

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