Figure 4: MiR-124 inhibits integrin αV subunit expression. | Scientific Reports

Figure 4: MiR-124 inhibits integrin αV subunit expression.

From: MiR-124 inhibits the migration and invasion of human hepatocellular carcinoma cells by suppressing integrin αV expression

Figure 4

(A) Representative micrographs of phase contrast and fluorescence microscope in SMMC-7721 and BEL-7404 cells infected by miR-124 or control lentivirus carrying GFP (left). Expression of miR-124 was measured by RT-PCR (middle) and quantitative RT-PCR (right). (B) Expression measurement of Sp1 and integrin αV by RT-PCR (upper) and quantitative analysis (lower). (C) Expression measurement of Sp1 and integrin αV by WB (upper) and quantitative analysis (lower). (D) Expression measurement of Sp1 and integrin αV by qRT-PCR in cells transfected with miR-124 inhibitor. (E) Representative micrographs of transmembrane migration and quantitative analysis. Original magnification:20×. Data are representative of three independent experiments. **p < 0.01.*p < 0.05.

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