Figure 1: Sequence similarities between ATOM14/Tom22 and Tom22/Tom9 and predicted domain structures of the proteins. | Scientific Reports

Figure 1: Sequence similarities between ATOM14/Tom22 and Tom22/Tom9 and predicted domain structures of the proteins.

From: Mitochondrial protein import - Functional analysis of the highly diverged Tom22 orthologue of Trypanosoma brucei

Figure 1

(A) Top, alignment of Tom22 of S. cerevisiae (blue) with ATOM14 of T. brucei (black). Bottom, alignment of Tom22 (blue) with Tom9 of A. thaliana (green). Both alignments were produced using HHPred. Identical residues in the Tom22-ATOM14 or the Tom22-Tom9 alignments are indicated by red boxes. Identical residues present in all three proteins (Tom22/ATOM14/Tom9) are shown in the large red boxes. The transmembrane segment predicted by the HMMTOP server (http://www.enzim.hu/hmmtop/) is indicated by the cross-hatched box. (B) Cartoon of all ATOM14 (grey bar), Tom22 (white bar) and Tom9 (black bar) (fusion)-proteins and their designations used in this study. Crosshatched box: predicted transmembrane domain.

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