Figure 3: BORIS expression affected colorectal cancer cell proliferation.
From: Brother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer
(a) Colorectal cell viability was determined by using the MTT assay. Dashed lines indicate the growth of control siRNA-and pVector-transfected cells. Solid lines indicate the growth of BORIS siRNA-and pBORIS-transfected cells. (b) The colony formation ability of two colorectal cancer cell lines was assessed by crystal violet staining 7 days after siRNA transfection. The right panel indicates the percentage of signal in each well compared to that in the control siRNA-transfected cells. Statistical differences between the control and treatments were evaluated by two-tailed Student’s t-test. ***p < 0.001.
