Figure 7: BORIS but not BORIS-ZFdel inhibits apoptosis induced by 5-FU.
From: Brother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer
(a) Cytochrome c immunofluorescence staining of 5-FU-treated Caco-2 cells with overexpression of pVector, pBORIS or pBORIS-ZFdel. The secondary antibody conjugated with FITC indicated the release of cytochrome c. The right panel indicates the fold change of immunofluorescence staining signals. (b) PI staining of the DNA content indicates difference in cell cycles under treatment with 5-FU.
