Table 1 Summary of clinical signs and EAE disease burden after adoptive transfer of AAMϕs from T. crassiceps-infected mice.

From: Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis

 

PBS (control)

Tc-Μϕs

Δ/control

* p-value

% EAE

100.0

80.0

−20.0%

n/a

Average Day of Onset ± SD

13.00 ± 0.71

15.80 ± 0.84

2.8 Days

0.0107

Mean Score D18

3.65 ± 0.34

1.40 ± 1.14

−2.25

0.0114

Area Under the Curve

14.7 ± 3.25

3.25 ± 2.57

−11.45

0.0079

Max Score

4

3

−1

n/a

Mean Weight D10–18

17.0 ± 1.8

18.9 ± 0.7

+1.9 g

0.0013

Mean Weight D18

15.2 ± 0.8

18.3 ± 2.1

+3.1 g

0.0126

n

5

5

n/a

n/a

  1. *Statistics tests. Day of Onset, Mean Score and AUC: Mann-Whitney or Unpaired t-test. Mean Weights: Unpaired t-test.
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