Figure 2: Effect of CCT on fibrillation of α-synuclein A53T deletion mutants. | Scientific Reports

Figure 2: Effect of CCT on fibrillation of α-synuclein A53T deletion mutants.

From: The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction

Figure 2

(a) Scheme of full-length α-syn A53T and the deletion mutants used for fibrillation experiments. (b) Fibrillation kinetics of the α-syn A53T deletion mutants in the presence of ADP and different molar ratios of CCT, measured by ThT fluorescence. As a control, the fluorescence of CCT in the absence of α-syn A53T was also tested.

Back to article page