Table 3 Receiver operating characteristic curves for quantitative and qualitative parameters in the differentiation between benign and malignant lesions.

From: Qualitative and quantitative analysis with a novel shear wave speed imaging for differential diagnosis of breast lesions

Variables

 

Cut-off value

Sensitivity (%)

Specificity (%)

Accuracy (%)

PPV (%)

NPV (%)

AUROC

95%CI

P

Emean

kPa

36.05

85.1 (40/47)

96.6 (172/178)

94.2 (212/225)

87.0 (40/46)

96.1 (172/179)

0.943

0.896–0.990

<0.001

m/s

3.30

85.1 (40/47)

95.5 (170/178)

93.3 (210/225)

83.3 (40/48)

96.0 (170/177)

0.931

0.882–0.981

<0.001

ESD

kPa

17.90

93.6 · (44/47)

97.8 · (174/178)

96.9 · (218/225)

91.7 · (44/48)

98.3 · (174/177)

0.936

0.866–1.000

<0.001

m/s

0.91

93.6 (44/47)

95.5 (170/178)

95.1 (214/225)

84.6 (44/52)

98.3 (170/173)

0.936

0.866–1.000

<0.001

Eratio

kPa

3.67

76.6 (36/47)

91.0 (162/178)

88.0 (198/225)

69.2 (36/52)

93.6 (162/173)

0.872

0.809–0.936

<0.001

m/s

1.87

76.6 (36/47)

91.0 (162/178)

88.0 (198/225)

69.2 (36/52)

93.6 (162/173)

0.863 *

0.794–0.932

<0.001

Color pattern

 

2–3

89.4 (42/47)

97.2 (173/178)

95.6 (215/225)

89.4 (42/47)

97.2 (173/178)

0.957

0.914–1.000

<0.001

  1. Emean = the mean elasticity; ESD = standard deviation of the elasticity; Eratio = the ratio elasticity; PPV = positive predictive value; NPV = negative predictive value; CI = confidence interval; AUROC = area under the receiver operating characteristic curve.
  2. *There are statistically significant difference between AUROC of color patterns and Eratio in speed mode (P = 0.03 < 0.05).
  3. ·ESD expressed in KPa obtained the highest Sensitivity, Specificity, Accuracy, PPV, NPV compared with the Eratio with statistically significant difference. (Corresponding P = 0.008 for Sensitivity comparison, P = 0.002 for Specificity comparison, P = 0.000 for Accuracy comparison, P = 0.006 for PPV comparison, P = 0.030 for NPV comparison, all P < 0.05).
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