Figure 4: Network figure for tolerance.

(The node sizes correspond to the number of trials that investigated the treatments. Directly comparable treatments are linked with a line, and the thickness of the line corresponds to the sample size in each pairwise treatment comparison. The “References” at the upper right corner displays three different nodes sizes correspond to three different levels of sample size of placebo and active drugs, three different lines thickness correspond to the three levels of different sample size of each pairwise treatment comparison).