Table 1 The comparison of plaques characteristics in different cohorts of APP/PS1 transgenic mice after the PP-3copy-Aβ1-6-loop123 treatment.

From: Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease

Group

Treatment age (month)

Plaque number in hippocampus (%)

Plaque number in cerebral cortex (%)

Plaque area in hippocampus (%)

Plaque area in cerebral cortex (%)

Before the onset of AD

4–9

−48.73

−49.10

−55.53

−37.32

Directly after the onset of AD

6–11

−65.52

−46.6

−70.31

−67.93

Long after the onset of AD

9–14

−23.91

−26.80

−41.05

−14.63

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