Table 4 Comparison of mycobacterial SDR protein and cofactor surface area with other NAD- and NADP-dependent dehydrogenases.
From: Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
Species | PDB ID | Protein surface area (A2) | Cofactor total surface area (A2) | Cofactor solvent accessible surface area (A2) |
---|---|---|---|---|
M. abscessus | 3S55 | 11,341 | 839 | 12 |
M. avium | 3T7C | 12,365 | 839 | 21 |
M. avium | 3UVE | 12,334 | 834 | 28 |
M. avium | 4RGB | 11,338 | 842 | 7 |
M. avium | 3PXX | 11,686 | 841 | 14 |
M. avium | 5EJ2 | 11,728 | 852 | 26 |
M. paratuberculosis | 3PGX | 11,168 | 835 | 19 |
M. paratuberculosis | 3SX2 | 11,320 | 842 | 7 |
M. paratuberculosis | 3TSC | 11,472 | 840 | 26 |
Average mycobacterial SDRs | Â | 11,639 | 840 | 18 |
Acholeplasma laidlawii | 4NBT | 10,890 | 842 | 99 |
Xanthobacter autotrophicus | 4ITU | 10,608 | 849 | 64 |
Homo sapiens | 4CQM | 11,373 | 837 | 72 |
Helicobactor pylori | 4IIN | 10,545 | 836 | 160 |
Bacillus sp. Sg-1 | 4NBU | 11,127 | 840 | 48 |
Average NAD-bound dehydrogenases | Â | 11,015 | 841 | 89 |
Staphylococcus aureus | 3SJ7 | 11,371 | 928 | 106 |
Listeria monocytogenes | 4JRO | 11,057 | 902 | 103 |
Synechococcus elongatus | 4DMM | 10,985 | 927 | 64 |
Brassica napus | 1EDO | 10,757 | 911 | 64 |
Escherichia coli | 4IIU | 11,223 | 916 | 74 |
Average NADP-bound dehydrogenases | Â | 11,079 | 916 | 82 |