Figure 6: The effect of PTS on 6-OHDA-induced deficits in the locomotor behavior of zebrafish. | Scientific Reports

Figure 6: The effect of PTS on 6-OHDA-induced deficits in the locomotor behavior of zebrafish.

From: Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways

Figure 6

Zebrafish at 3 day post fertilization were exposed to indicated concentrations of PTS or Nom with or without 0.25 mM 6-OHDA for 4 days. Then zebrafish were collected and the locomotor activity of each group was monitored using the Viewpoint Zebrabox system; total distance traveled in 10 min was calculated. (A) Representative patterns of zebrafish locomotion traced from control and different treatment groups. (B) Statistical analysis of total distance moved of different treatment groups, eight fish larvae/group from three independent experiments. ###P < 0.01 versus CTL group, **P < 0.01 versus 6-OHDA-treated group.

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