Figure 7: Summary of the variation of metabolic pathways induced by HBc. | Scientific Reports

Figure 7: Summary of the variation of metabolic pathways induced by HBc.

From: Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells

Figure 7

Metabolites and enzymes shown in red indicate higher expression levels and direct interaction with HBc or MLX. Enzymes without significant changes are marked in blue. *PGK1 expression was significantly increased in the proteomics data, but the interaction between PGK1 and MLX is still unclear. Abbreviations: G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; 3 PG, glyceraldehyde-3-phosphate; GC3P, 3-phosphoglyceric acid; PEP, phosphoenolpyruvate; OAA, oxaloacetate; 3PHP, 3-phosphohydroxypyruvate; P-serine, phosphatidylserine; 2-OG, 2-oxoglutarate; THF, tetrahydrofolate; me-THF; 5,10-methylene-THF; F-THF, 10-formyltetrahydrofolate; GSH, glutathione.

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