Table 1 Histopathological damage evaluation in HIF-1α interfered rats.

From: HIF-1α induction during reperfusion avoids maladaptive repair after renal ischemia/reperfusion involving miR127-3p

Histopathological damage

 

Scrambled

HIF-1α siRNA

Sham

−

−

Ischemia

+

++

R-3d

+

++++

R-5d

++

+++

R-7d

+

+

  1. Histopathological damage was evaluated as double-blind study based on the following characteristics: (1) Morphological changes in proximal tubular epithelium: necrotic cells, brush border loss, cell detachment; (2) Infiltrate presence; (3) Hyaline cylinders presence. (4) Other alterations also considered were: tubular dilatation, interstitial edema and medular congestion.
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