Figure 4: Effect of zeta potential on the uptake of docosanoic acid SLNs with similar sizes entrapped enrofloxacin in RAW.264.7 cells.

The −24.9 mv SLNs were prepared with 0.2 g enrofloxacin, 1.8 g docosanoic acid, and 10 ml 1% PVA. The −17.5 mv SLNs were prepared with 0.2 g enrofloxacin, 1.8 g docosanoic acid, and 20 ml 2% PVA and 0.5% DDAC. The −8.1 mv SLNs were prepared with 0.2 g enrofloxacin, 1.8 g docosanoic acid, and 20 ml 2% PVA and 2% DDAC. The 7.1 mv SLNs with 501 nm were prepared with 0.2 g enrofloxacin, 1.8 g docosanoic acid, and 20 ml 2% PVA and 3% DDAC. aStatistical significances compared with −24.9 mv are p < 0.05.