Table 1 Physicochemical characteristics of enrofloxacin-loaded docosanoic acid SLNs with different polyvinyl alcohol concentration and preparation process (mean ± S.D., n = 3).

From: Enhanced intracellular delivery and antibacterial efficacy of enrofloxacin-loaded docosanoic acid solid lipid nanoparticles against intracellular Salmonella

Surfactant

Probe Sizes (mm)

MD (nm)

PDI

ZP (mv)

EE (%)

LC (%)

PVA concentration

PVA volume (mL)

1%

10

3

605.0 ± 4.9

0.241 ± 0.076

−24.9 ± 0.7

95.9 ± 1.6

9.3 ± 0.2

2%

20

6

414.5 ± 3.8 a

0.265 ± 0.019

−22.1 ± 0.1 a

86.6 ± 1.7 a

8.6 ± 0.2

4%

30

30

150.1 ± 1.9 a , b

0.184 ± 0.018 b

−13.1 ± 1.0 a , b

59.2 ± 3.5 a , b

5.8 ± 0.4 a , b

  1. EE: Encapsulation efficiency; LC: Loading capacity; MD: Mean diameter; PDI: Polydispersity index; ZP: Zeta potential.
  2. aStatistical significances compared with 1% PVA are p < 0.05.
  3. bStatistical significances compared with 2% PVA are p < 0.05.
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