Figure 6: Albuminuria, renal function, and renal pathology in wild type or NLRP3 KO mice with IgAN.
From: NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy
Time-course study of the urine albumin and Cr ratio (a); BUN levels (b); serum Cr levels (c). Kidney histopathology (H&E staining) (d) on the indicated days, arrow indicates periglomerular mononuclear leukocyte infiltration, original magnification, 400x. Renal lesion scores (e). The data are expressed as the mean ± SEM for 7 mice per group. *p < 0.05; **p < 0.01; ***p < 0.005. WT, wild type. #Not detectable. ns, no significant difference.
