Figure 7: Infiltration of macrophages, DCs, or T cells of the kidney in wild type or NLRP3 KO mice with IgAN.
From: NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy
F4/80+ macrophages (a), CD11c+ DCs (b), or CD3+ T cells (c) detected by immunohistochemistry, arrow indicates positive staining, original magnification, 400x; Scoring of stained cells in the glomerulus and periglomerular region (d-f). The data are expressed as the mean ± SEM for 7 mice per group. *p < 0.05; **p < 0.01; ***p < 0.005. WT, wild type. #Not detectable. ns, no significant difference. gcs, glomerular cross section.
