Figure 6: Effect of LY294002 on Akt phosphorylation and renal expression of mitochondria apoptotic proteinsin the kidneys of glycerol-induced AKI with MSCs treatment. | Scientific Reports

Figure 6: Effect of LY294002 on Akt phosphorylation and renal expression of mitochondria apoptotic proteinsin the kidneys of glycerol-induced AKI with MSCs treatment.

From: Biological Membrane-Packed Mesenchymal Stem Cells Treat Acute Kidney Disease by Ameliorating Mitochondrial-Related Apoptosis

Figure 6

(a) The results of western blotting indicated that LY294002 significantly reduced MSC-induced phosphorylation of p-Akt. (b) The analytic outcomes show that LY294002 pretreatment significantly increased Bad, Cytochrome c, cleaved caspase-9, and cleaved caspase-3 and decreased Bcl-xl compared with those of the MSC group. Note: *p < 0.05, n = 6.

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