Table 5 Operative characteristics included in the multi-variable model, and their association with 28-day mortality.

From: A UK wide cohort study describing management and outcomes for infants with surgical Necrotising Enterocolitis

Operative Characteristic

Died n(%)

Alive n(%)

Odds Ratio (95% CI)

Adjusted Odds Ratio (95% CI)*

Ileo-caecal valve resected

Yes

2 (6%)

38 (21%)

0.2 (0.03–0.96, p = 0.03)

0.2 (0.04–1.4)

No

34 (94%)

147 (79%)

Definitive diagnosis of SIP at laparotomy

Yes

7 (19%)

25 (14%)

1.5(0.5–4.1, p = 0.35)

3.1 (1.05–9.3)

No

29 (81%)

160 (86%)

Operation performed

Resection and primary anastomosis

2 (6%)

38 (21%)

1 (reference)

1 (reference)

Resection and stoma formation

12 (33%)

108 (59%)

2.1 (0.45–9.9, p = 0.34)

2.4 (0.5–12.1)

Stoma formation, no resection

7 (19%)

30 (16%)

4.4 (0.86–22.9, p = 0.08)

4.5 (0.8–26)

Clip and drop with resection

5 (14%)

5 (3%)

19 (2.9–125.3, p = 0.002)

30 (3.9–237)

Open and close laparotomy

10 (28%)

0 (0%)

Not calculable

Not calculable

Negative initial laparotomy

0 (0%)

2 (11%)

Not calculable

Not calculable

  1. *Complete case analysis was used for development of the final model, and therefore data from 17 of the 224 infants who underwent a laparotomy (7.5%) were not used in its development.
  2. SIP – Spontaneous Intestinal Perforation.