Figure 5: Genomic island dedicated to natural products in Planktothrix.

Similar genomic islands containing biosynthetic gene clusters of apt (green), oci (red) and mdn (blue) were found in P. sp. PCC 11201, P. rubescens PCC 7821 identical to the one found in nine planktonic Planktothrix spp. (NIVA-CYA 15, NIVA-CYA 34, NIVA-CYA 56/3, NIVA-CYA 98, NIVA-CYA 126/8, NIVA-CYA 405, NIVA-CYA 406, NIVA-CYA 407 and NIVA-CYA 540) and in P. agardhii PCC 7805. In the latter, the genomic island is not evidenced by the current assembly of the contigs, but one remaining gene of apt and the flanking regions witness a previous occurrence of the same genomic island organization. Clusters with conserved sequence and domain organization are connected in grey and in black when reorganized. The genetic island in addition of apt, oci and mdn gene clusters contained other genes putatively involved in these pathways (in grey), flanking genes (in white) and genes of mobility such as insertion sequences and transposases (in yellow).