Figure 3: Stability prediction of TK variants by Rosetta.
From: Two strategies to engineer flexible loops for improved enzyme thermostability
(A) Heat map of ΔΔG values for TK variants showing stable (red) and unstable (green) variants. Black squares highlight the variants generated and tested experimentally. (B) Correlation between ΔΔG values and residual activity (relative to wild type) of 41 TK consensus variants in lysates.
