Figure 1: The effect of miR-27a rs895819 A/G SNP on the mature miR-27a expression in vivo and vitro.

(A) Kaplan–Meier survival curve analysis with the different genotypes of miR-27a rs895819 (GG + AG vs. AA) for the subgroup for TNM I-II stage. (B) Kaplan–Meier survival curve analysis with the different genotypes of miR-27a rs895819 (AG vs. AA) for the subgroup for TNM I-II stage. (C) Kaplan–Meier survival curve analysis with the different genotypes of miR-27a rs895819 (GG + AG vs. AA) for the subgroup for lymph node metastasis (−). (D) The cell mature miR-27a expression transinfected by different miR-27a rs895819 plasmid. *P = 0.05.