Table 6 The effect of miR-27a rs895819 polymorphism to its mature miR-27a expression.

From: MiR-27a rs895819 is involved in increased atrophic gastritis risk, improved gastric cancer prognosis and negative interaction with Helicobacter pylori

 

Serum expression

Tissue expression in situ

Cancer

Controls

Cancer Tissue

Noncancer Tissues

n

Mean ± SD

n

Mean ± SD

n

Mean ± SD

 

n

Mean ± SD

Total

87

2.12 ± 1.14

83

1.46 ± 0.73

31

8.71 ± 0.37

32

8.55 ± 0.31

 Pa

<0.001

0.063

Genotype

 AA

38

2.25 ± 1.13

 

44

1.57 ± 0.78

14

8.84 ± 0.40

 

16

8.53 ± 0.32

 AG

47

2.01 ± 1.14

 

34

1.33 ± 0.71

16

8.64 ± 0.30

 

16

8.56 ± 0.30

 GG

2

2.02 ± 1.90

 

5

1.35 ± 0.18

1

8.18

 

0

NA

 Pb

 

0.630

  

0.340

 

0.103

  

0.744

  1. Note: aMeans the dependent sample-t test was used to calculate the difference betweenthe expressions of tumor and controls; bMeans the variance analysis was used to calculate the difference between the expressions of three genotypes.
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