Figure 1: M. minutoides SRY has a degraded C-terminal polyQ tract.
From: Reduced Activity of SRY and its Target Enhancer Sox9-TESCO in a Mouse Species with X*Y Sex Reversal
(a) PCR amplification of the full-length Sry coding region from M. minutoides or M. mattheyi. An M. musculus sample was included as a control. (b) Schematic of SRY proteins from three Mus species: M. musculus (musSRY), M. mattheyi (matSRY), and M. minutoides (minSRY). Brg, bridge domain. Numbers indicate the sequence identity scores compared to the same domain of musSRY. (c) Alignment of the deduced amino acid sequences of the C-terminal polyQ tract of SRY from the three Mus species. Glutamine blocks are highlighted in grey.
