Figure 3: Brain metastasis regression analyses for the 4 tumour groups: tumour, tum+FLX, tum+SSZ, tum+5-ASA/SP. | Scientific Reports

Figure 3: Brain metastasis regression analyses for the 4 tumour groups: tumour, tum+FLX, tum+SSZ, tum+5-ASA/SP.

From: Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression

Figure 3

(A) Brain metastases were not predictive of sucrose preference for any of the tumour groups. (B) Brain metastases were predictive of lower FST immobility time for mice treated with SSZ (P = 0.019). (C) Brain metastases were predictive of lower immobility time for untreated tumour-bearing mice (P = 0.005). (D) Brain metastases were predictive of higher PM for untreated tumour mice (P = 0.004) and 5-ASA/SP treated mice (P = 0.013). Results were analyzed using linear regression analyses. *P < 0.05, **P < 0.001.

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