Table 1 Summary of results for behavioural and cytokine analyses.

From: Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression

Comparison

SPT

FST

TST (Immob.)

TST (P.M.)

Serum Glu

IL-1β

IL-6

IL-17A

TNF-α

Control vs. Tumour

Tumour vs. Tum+FLX

Tumour vs. Tum+SSZ

↑↑

Tumour vs. Tum+5-ASA/SP

  1. “−”Denotes no differences between groups. One arrow denote a mean difference between groups with 0.05 > P > 0.01. Two arrows denote a mean difference between groups with P < 0.01. The direction of the arrows represents the direction of change of mean for that particular measure. SPT, sucrose preference test; TST, tail suspension test; FST, forced swim test; FLX, fluoxetine; SSZ, sulfasalazine; 5-ASA, 5-aminosalicylic acid; SP, sulfapyridine; Glu, glutamate; IL, interleukin; TNF-α, tumour necrosis factor-α.