Figure 5: DHCR24 expression level is negatively correlated with PGR expression level. | Scientific Reports

Figure 5: DHCR24 expression level is negatively correlated with PGR expression level.

From: Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma

Figure 5

(A) The correlation between the expression level of DHCR24 and PGR was analyzed in the TCGA dataset of EC (R = −0.395, p = 0.006). (B) The correlation between the expression levels of DHCR24 and PGR was analyzed in the GEO dataset of EC (R = −0.318, p = 0.0021). (C) The correlation between the expression levels of DHCR24 and PGR was analyzed in the EC cell lines (R = −0.775, p < 0.05). (D) mRNA expression level of DHCR24 and PGR under DHCR24 siRNA interference. (E) Representative images of the immunohistochemical staining for DHCR24 and PGR in paraffin continuous sections of Grade I endometrial cancer. (F) Representative images of immunohistochemical staining for DHCR24 and PGR in paraffin continuous sections in Grade III endometrial cancer. Scale bar 50 μm.

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