Figure 4: Scatter plot and linear regression showing a statistically significant correlation between population doublings at time of senescence and the percentage BrdU positive cells at 22–25 population doublings (p = 3.07 × 10−4). | Scientific Reports

Figure 4: Scatter plot and linear regression showing a statistically significant correlation between population doublings at time of senescence and the percentage BrdU positive cells at 22–25 population doublings (p = 3.07 × 10−4).

From: Characterisation of a divergent progenitor cell sub-populations in human osteoarthritic cartilage: the role of telomere erosion and replicative senescence

Figure 4

Pearson’s product-moment correlation = 0.74. Blue points show N-CPC samples (long telomeres), orange points show OA-CPCs that had long telomeres, grey points show OA-CPCs with short telomeres and black points show OA-CPCs for which no telomere data was available. Long telomere samples have prolonged replicative and proliferative capacity as indicated by population doublings and BrdU.

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