Figure 7: The average telomere length of all chromosomes was investigated using qPCR. | Scientific Reports

Figure 7: The average telomere length of all chromosomes was investigated using qPCR.

From: Characterisation of a divergent progenitor cell sub-populations in human osteoarthritic cartilage: the role of telomere erosion and replicative senescence

Figure 7

(A) Telomere length was 38% lower in ES-OA-CPCs compared to N-CPCs (p = 0.0026) and 41% shorter compared with LS-OACPCs (p = 0.0017). Statistical significance (*) was shown using Anova with Tukey’s HSD pair-wise comparisons. (B) Average telomere length at 22–25 population doublings correlates with the number population doubling at senescence. Pearson’s product-moment correlation coefficient = 0.74, (p = 7.2 × 10−4). Shorter telomeres are predictive of ES-OA-CPCs and longer telomeres predictive of LS-OA-CPCs.

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