Figure 1: miR-199a-5p is up-regulated in human osteosarcoma tissues and cell lines.
From: MicroRNA-199a-5p promotes tumour growth by dual-targeting PIAS3 and p27 in human osteosarcoma
(A) The relative miR-199a-5p expression in each human osteosarcoma (OS) tissue compared with its paired normal adjacent tissue (NAT) shown as histograms. (B) The overall miR-199a-5p expression in the eight human OS and NAT samples shown as box-and-whiskers plots (P = 0.0025). (C) The relative miR-199a-5p expression in four human osteosarcoma cell lines (Saos-2, MNNG/HOS, MG63 and 143B) compared with the human osteoblast cell line hFOB 1.19. miR-199a-5p expression was analysed using qRT-PCR, and U6 snRNA was used as an internal control. The data are expressed as the means ± SEM, **P < 0.01.
