Table 3 KP and Immune profile changes between baseline and 2 years follow-up in Cohort 2 patients with RRMS.
Variables (n) | Baseline, median (quartiles) | Follow-up, median (quartiles) | Fold Change | p-value |
|---|---|---|---|---|
K/T ratio (44) | ||||
RRMS | 54 (40, 65) | 57 (47, 71) | 0.06 | 0.029 |
SPMS | 44 (39, 77) | 56 (38, 95) | 0.27 | >0.05 |
IL-2 (24) | ||||
RRMS | 17 (3, 41) | 4 (2, 11) | −0.76 | 0.011 |
SPMS | 9 (2, 16) | 3 (1, 7) | −0.67 | >0.05 |
IL-7 (40) | ||||
RRMS | 13 (9, 19) | 18 (13, 25) | 0.38 | 0.024 |
SPMS | 14 (11, 23) | 20 (14, 24) | 0.43 | >0.05 |
MIP-1α (28) | ||||
RRMS | 5 (4, 10) | 10 (5, 13) | 1.00 | 0.004 |
SPMS | 10 (4, 12) | 9 (7, 12) | −0.10 | >0.05 |
MIP-1β (41) | ||||
RRMS | 37 (21, 71) | 69 (48, 90) | 0.86 | 0.001 |
SPMS | 42 (28, 94) | 71 (48, 108) | 0.69 | >0.05 |
