Figure 5: PDGFRα+ MSCs are induced in the T + D group. | Scientific Reports

Figure 5: PDGFRα+ MSCs are induced in the T + D group.

From: Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice

Figure 5

(A) The tissue lysates of the SSP muscle collected from surgically treated and sham-operated specimens (2 biological replicates) were subjected to Western blotting using anti-PDGFRα (upper panel) and anti-GAPDH antibodies (lower panel). (B) Immunofluorescent images of the SSP muscle sections stained for laminin and PDGFRα and with DAPI. Representative images of 3 biological replicates are shown. Bar, 30 μm. (C) The number of PDGFRα-positive cells per microscopic field (214 μm × 214 μm) of SSP muscle section. The values represent the means ± S.D. n = 3 mice. Three different sections were analyzed in each specimen. ****p < 0.0001.

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