Figure 2: Impairment of AP-2 expression leads to a reduction in neuronal process. | Scientific Reports

Figure 2: Impairment of AP-2 expression leads to a reduction in neuronal process.

From: Adaptor Protein 2 (AP-2) complex is essential for functional axogenesis in hippocampal neurons

Figure 2

(a–d) The lengths of individual branch of axon were measured using four markers (EGFP. GFP-Tau, GFP-VAMP2 and GFP-Synapsin I). AP-2 depleted neurons have significantly deficient axon extension in each axon branch. (e–h) Sholl analysis was applied in WT, AP-2KD, and rescued neurons transfected four different markers. AP-2KD neuron has significantly decreased neuronal process (<40 μm) as measured by all four different markers compare to that of WT or rescued neurons (~100 μm).

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