Figure 1: The IL-32 promoter SNP.

(A) Location of the IL32 promoter SNP within the IL32 region on chromosome 16. (B) Genotype frequencies of the IL32 rs4786370 promoter SNP in individuals from the NN cohort (NN; CC:19.2%, CT:45.7%, TT:35%), RA patients from the Radboudumc Nijmegen (RA1; CC:16.1%, CT:51%, TT:32.9%) and RA patients from the Reade clinic Amsterdam (RA2; CC:23%, CT:47.1%, TT:29.9%). Total number of patients per cohort; NN:#234, RA1:#292, RA2:#348. Chi-square analysis (IBM SPSS Statistics v.22) showed no significant differences in genotype distribution between the cohorts.