Table 2 Pooled ORs and 95%CIs of the associations between three polymorphisms in ADIPOQ gene and hypertension risk.
Genetic model | NO. of studies | OR | 95%CI | Pmeta-analysis | Bon | FDR | Statistical method | I2 (%) | Paheterogeneity |
|---|---|---|---|---|---|---|---|---|---|
rs2241766 | |||||||||
G VS T | 12 | 1.16 | 1.06–1.27 | 0.002 | 0.010 | 0.007 | Fixed | 22.90 | 0.218 |
GG VS GT + TT | 12 | 1.34 | 1.10–1.63 | 0.004 | 0.020 | 0.007 | Fixed | 0.00 | 0.597 |
GG + GT VS TT | 12 | 1.15 | 1.02–1.30 | 0.024 | 0.120 | 0.030 | Fixed | 24.20 | 0.206 |
GT VS TT | 12 | 1.09 | 0.96–1.23 | 0.204 | 1.000 | 0.204 | Fixed | 25.00 | 0.196 |
GG VS TT | 12 | 1.38 | 1.12–1.69 | 0.003 | 0.015 | 0.007 | Fixed | 0.00 | 0.457 |
rs1501299 | |||||||||
T VS G | 9 | 0.98 | 0.88–1.08 | 0.646 | 1.000 | 0.838 | Fixed | 28.90 | 0.188 |
TT VS TG + GG | 9 | 1.05 | 0.84–1.32 | 0.670 | 1.000 | 0.838 | Fixed | 33.50 | 0.15 |
TT + TG VS GG | 9 | 0.95 | 0.83–1.08 | 0.404 | 1.000 | 0.838 | Fixed | 0.00 | 0.458 |
TG VS GG | 9 | 0.94 | 0.82–1.08 | 0.363 | 1.000 | 0.838 | Fixed | 0.00 | 0.647 |
TT VS GG | 9 | 1.00 | 0.79–1.26 | 0.988 | 1.000 | 0.988 | Fixed | 37.50 | 0.119 |
rs266729 | |||||||||
G VS C | 5 | 1.10 | 0.94–1.28 | 0.219 | 1.000 | 0.365 | Fixed | 29.70 | 0.224 |
GG VS GC + CC | 5 | 1.43 | 1.02–2.01 | 0.040 | 0.200 | 0.140 | Fixed | 49.00 | 0.098 |
GG + GC VS CC | 5 | 1.04 | 0.86–1.26 | 0.704 | 1.000 | 0.732 | Fixed | 19.70 | 0.289 |
GC VS CC | 5 | 0.96 | 0.79–1.18 | 0.732 | 1.000 | 0.732 | Fixed | 41.90 | 0.142 |
GG VS CC | 5 | 1.41 | 0.99–2.00 | 0.056 | 0.280 | 0.140 | Fixed | 44.20 | 0.127 |
