Figure 3: Effect of the lack of galectin-3 on the neuronal survival in cortex and hippocampus after TBI. | Scientific Reports

Figure 3: Effect of the lack of galectin-3 on the neuronal survival in cortex and hippocampus after TBI.

From: Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration

Figure 3

Chart comparing the expression of galectin-3 between wild type and galectin-3 knockout mice in the ipsilateral cortex 24 h after injury (a). Comparison of NeuN-positive cells between wild type and galectin-3 knockout mice after TBI in the cortex (b), CA1 (c) and dentate gyrus (d). Representative pictures of NeuN in different regions (e). Representative image of toluidine blue staining in wild type and galectin-3 knockout mice (f) and quantification of the cortical tissue loss (g) 21 days after injury. Statistics and error bars: mean ± s.d. n = 4 for (a–d) and (g). Data were analysed using two-sided student’s t-test. *p < 0.05 **p < 0.01 and ****p < 0.0001. Scale bar in e is 100 μm and for f is 1000 μm.

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