Table 3 Hazard ratios of disease recurrence.
Genotype | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
no BRAF, no TERT | 1.000 | 1.000 | 1.000 | 1.000 | ||||||||
BRAF mut only | 0.696 | 0.141–3.450 | 0.658 | 0.578 | 0.114–2.930 | 0.508 | 0.676 | 0.135–3.398 | 0.635 | 0.626 | 0.125–3.139 | 0.569 |
BRAF/TERT mut | 6.740 | 2.173–20.905 | 0.001 | 4.172 | 1.011–17.218 | 0.048 | 3.016 | 0.659–13.797 | 0.155 | 4.068 | 0.966–17.129 | 0.056 |
Adjustment | age, sex, N | age, sex, size | age, sex, Ex | |||||||||
Ki67 labeling index | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | |||
<5% | 1.000 | 1.000 | 1.000 | |||||||||
5–10% | 2.444 | 0.611–9.779 | 0.207 | 2.620 | 0.650–10.563 | 0.176 | 2.247 | 0.547–9.222 | 0.261 | |||
>10% | 9.871 | 3.422–28.476 | <0.001 | 8.131 | 2.718–24.323 | <0.001 | 5.521 | 1.719–17.737 | 0.004 | |||
Adjustment | age, sex, N | age, sex, N, size, Ex | ||||||||||
Risk group | HR | 95% CI | p-value | HR | 95% CI | p-value | ||||||
Low | 1.000 | 1.000 | ||||||||||
Low vs. Middle | 10.147 | 2.859–36.012 | 3.36E-04 | 8.795 | 2.349–32.924 | 0.001 | ||||||
Middle vs. High | 11.762 | 3.636–38.048 | 3.87E-05 | 6.255 | 1.134–34.505 | 0.035 | ||||||
Adjustment | age, sex, size, Ex | |||||||||||
