Figure 2: ASIV suppresses histological injury in TNBS-induced colitis in rats.

(A) Representative images of HE staining of colon tissue from different groups (a1-a5). Bar = 100 μm. The area within the rectangle in each picture is enlarged and presented below, correspondingly, to display the mucosa (b1-b5) and submucosa (c1-c5) in each group. Bar = 10 μm. (B) Colonic histological score. Sham: sham group; ASIV: ASIV alone group; TNBS 1D: TNBS treatment for 1 day group; TNBS 7D: TNBS treatment for 1 days followed by saline treatment for 6 days group; TNBS 7D + ASIV: TNBS treatment for 1 day followed by ASIV treatment for 6 days group. Data are mean ± SEM (N = 8). *p < 0.05 vs. Sham group, #p < 0.05 vs. TNBS 7D group.