Figure 6: Decreased expression of P-Selectin in human SLE biopsies.
From: P-Selectin preserves immune tolerance in mice and is reduced in human cutaneous lupus
(a) Representative photomicrographs (20×) of anti-CD31 and anti-P-Selectin stained skin biopsies of healthy donors and SLE patients (upper panels). Black arrows point blood vessels. (b) 200% magnification of representative blood vessels from the original images are represented (lower panels). (c) Classification and quantification of CD31+ dermal blood vessels according to the expression level of P-Selectin (healthy controls, n = 4; SLE patients, n = 4); bars show the mean ± SD. **p < 0.01 by Student’s two tailed t test.
