Figure 2
From: Mechanisms underlying the cardiac antifibrotic effects of losartan metabolites
Histograms represent the expression of cardiac TGF-β1 (panel A) and CTGF (panel B) mRNA and CTGF protein (panel C) in the myocardium of Vehicle-, EXP3179-, EXP3174-, L-NAME + Vehicle-, L-NAME + EXP3179- and L-NAME + EXP3174-treated rats. Representative Western blot autoradiograms for CTGF are presented at the bottom of panel C. Bars represent mean + SEM (n = 10). *P < 0.05 vs Vehicle, EXP3179 and EXP3174, †P < 0.05 vs L-NAME + Vehicle, #P < 0.05 vs Vehicle and L-NAME + Vehicle.
