Figure 4
From: Mechanisms underlying the cardiac antifibrotic effects of losartan metabolites
Histograms represent the fold change in the expression of LOX mRNA (panel A), LOX protein (panel B) and collagen cross-linking (panel C) in the myocardium of Vehicle-, EXP3179-, EXP3174-, L-NAME + Vehicle-, L-NAME + EXP3179- and L-NAME + EXP3174-treated rats. Representative Western blot autoradiograms for LOX protein expression are presented at the bottom of panel B. Bars represent mean + SEM (n = 10). *P < 0.05 vs Vehicle, EXP3179 and EXP3174, †P < 0.05 vs L-NAME + Vehicle.
