Table 1 Specific activities of the α2βγ, αβ and αγ enzymes.

From: The β and γ subunits play distinct functional roles in the α2βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase

Enzyme

Specific activity (μmol/min/mg)

This work

Ehrlich et al.2

Soundar et al.19

Kim et al.22

α2βγ

20.2 ± 0.3

15–20

21.7

0.2359 ± 0.0320

αβ

3.33 ± 0.13

2.9

 

0.0046 ± 0.0002

αγ

7.27 ± 0.31

7.8

 

0.0255 ± 0.0007

  1. The specific activities of the enzymes were measured at the standard conditions: 33 mM Tris-acetate, pH 7.4, 80 mM ICT, 2 mM MnCl2, and 3.2 mM NAD.
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