Table 1 The twenty-three highest commonly differentially methylated CpGs in subcutaneous adipose tissue and leukocytes between obese (Ob) and non-obese (Nob) located in promoter and island and shore and sorted by gene name.
TargetID | CHR | Position | Gene name | Gene region | CpG context | Differences adipose tissue (Ob-Nob) | Differences leukocytes (Ob-Nob) |
|---|---|---|---|---|---|---|---|
cg02379560 | 4 | 40859280 | APBB2;APBB2;APBB2;APBB2;APBB2;APBB2;APBB2 | Body;TSS200;TSS200;Body;TSS200;Body;TSS200 | S_Shore | −0.11 | −0.07 |
cg20251225 | 1 | 1609551 | CDK11B;CDK11B;CDK11B;CDK11B;CDK11B;LOC728661;CDK11B | Body;Body;Body;Body;Body;5′UTR;5′UTR | S_Shore | −0.10 | −0.06 |
cg15681239 | 3 | 38080203 | DLEC1;DLEC1 | TSS1500;TSS1500 | N_Shore | −0.11 | −0.06 |
cg25932599 | 4 | 1005201 | FGFRL1;FGFRL1;FGFRL1 | TSS1500;TSS1500;TSS1500 | Island | −0.12 | −0.11 |
cg15644324 | 1 | 42384647 | HIVEP3;HIVEP3 | TSS200;TSS200 | S_Shore | 0.13 | 0.07 |
cg00514575 | 5 | 180231155 | MGAT1;MGAT1;MGAT1;MGAT1;MGAT1 | TSS1500;5′UTR;TSS1500;5′UTR;TSS1500 | S_Shore | −0.12 | −0.06 |
cg11201447 | 8 | 128808063 | MIR1204;PVT1 | TSS200;Body | S_Shore | −0.10 | −0.06 |
cg25152348 | 22 | 50946712 | NCAPH2;LMF2;NCAPH2;NCAPH2;NCAPH2 | 1stExon;TSS1500;5′UTR;5′UTR;1stExon | Island | −0.10 | −0.13 |
cg06936779 | 1 | 151171405 | PIP5K1A;PIP5K1A;PIP5K1A;PIP5K1A;PIP5K1A;PIP5K1A; PIP5K1A;PIP5K1A | 5′UTR;1stExon;5′UTR;1stExon;5′UTR;1stExon;1stExon;5′UTR | Island | −0.12 | −0.09 |
cg18437077 | 7 | 100860918 | PLOD3;PLOD3;ZNHIT1 | 1stExon;5′UTR;TSS200 | Island | −0.11 | −0.06 |
cg22712983 | 2 | 219187374 | PNKD;PNKD | TSS1500;Body | N_Shore | 0.12 | 0.10 |
cg02051077 | 7 | 131241343 | PODXL;PODXL;PODXL;PODXL | 5′UTR;1stExon;5′UTR;1stExon | Island | −0.11 | −0.07 |
cg11381564 | 6 | 32808619 | PSMB8;PSMB8 | 3′UTR;3′UTR | S_Shore | −0.14 | −0.08 |
cg14010720 | 20 | 62168878 | PTK6 | TSS200 | S_Shore | −0.13 | −0.06 |
cg10542975 | 11 | 67205096 | PTPRCAP;PTPRCAP | 5′UTR;1stExon | S_Shore | −0.15 | −0.06 |
cg02874908 | 11 | 67205113 | PTPRCAP;PTPRCAP | 5′UTR;1stExon | S_Shore | −0.12 | −0.09 |
cg17858911 | 12 | 123012351 | RSRC2;RSRC2;RSRC2;KNTC1 | TSS1500;TSS1500;TSS1500;5′UTR | S_Shore | −0.12 | −0.11 |
cg02996471 | 19 | 3178512 | S1PR4 | TSS1500 | N_Shore | −0.12 | −0.06 |
cg07496545 | 5 | 140683737 | SLC25A2 | TSS200 | Island | 0.12 | 0.05 |
cg07576222 | 15 | 67357975 | SMAD3 | TSS1500 | Island | −0.11 | −0.07 |
cg13104938 | 11 | 843956 | TSPAN4;TSPAN4;TSPAN4;TSPAN4;TSPAN4;POLR2L; TSPAN4;TSPAN4 | TSS1500;5′UTR;TSS200;5′UTR;5′UTR;TSS1500;5′UTR;5′UTR | S_Shore | 0.11 | 0.06 |
cg23713156 | 17 | 80606235 | WDR45L;WDR45L | 5′UTR;1stExon | Island | −0.10 | −0.09 |
