Table 2 Univariate and multivariate analysis for QFT positivity.

From: Association of Body Mass Index with the Tuberculosis Infection: a Population-based Study among 17796 Adults in Rural China

 

n/N (%)

p for χ2 test

Adjusted OR* (95% CI)

Study sites

 

<0.0001

 

 Site A

1052/5014(20.98)

 

Reference

 Site B

801/4141(19.34)

 

1.03(0.90–1.17)

 Site C

1173/4213(27.84)

 

1.34(1.19–1.51)

 Site D

847/3896(21.74)

 

1.37(1.21–1.56)

Gender

 

<0.0001

 

 Female

1793/9415(19.04)

 

Reference

 Male

2080/7849(26.50)

 

1.29(1.15–1.44)

Age (years)

 

<0.0001

 

 18–29

194/2344(8.28)

 

Reference

 30–39

313/2116(14.79)

 

1.81(1.47–2.22)

 40–49

876/4513(19.41)

 

2.46(2.04–2.96)

 50–59

934/3479(26.85)

 

3.81(3.16–4.58)

 60–69

966/3047(31.70)

 

4.97(4.10–6.04)

 ≥70

590/1765(33.43)

 

5.67(4.61–6.98)

Education level

 

<0.0001

 

 Primary school or lower

2175/8573(25.37)

 

Reference

 Middle school

1264/6044(20.91)

 

1.10(1.00–1.21)

 High school

367/2014(18.22)

 

1.06(0.92–1.22)

 College or higher

67/633(10.58)

 

0.95(0.71–1.26)

Smoking status

 

<0.0001

 

 Never smoked

2405/12176(19.75)

 

Reference

 Ever smoked

1468/5086(28.86)

 

1.28(1.15–1.43)

Alcohol drinking

 

<0.0001

 

 No

2877/13373(21.51)

 

Reference

 Yes

996/3890(25.60)

 

0.99(0.89–1.10)

History of close contact with TB patients

 

<0.0001

 

 No

3480/15826(21.99)

 

Reference

 Yes

221/708(31.21)

 

1.38(1.16–1.64)

History of T2DM

 No

3627/16396(22.12)

 

Reference

 Yes

246/868(28.34)

 

1.04(0.88–1.22)

Number of BCG scars

 0

2021/8891(22.73)

 

Reference

 1

1049/5030(20.85)

 

0.98(0.88–1.10)

 ≥2

803/3341(24.03)

 

1.05(0.93–1.20)

Cholesterol levela

 

<0.0001

 

 Normal

3168/14632(21.65)

 

Reference

 Higher than normal

704/2628(26.79)

 

1.04(0.92–1.19)

Triglyceride levelb

 

<0.0001

 

 Normal

2380/11072(21.50)

 

Reference

 Higher than normal

1492/6188(24.11)

 

1.04(0.96–1.13)

LDL levelc

 

<0.0001

 

 Normal

3117/14538(21.44)

 

Reference

 Higher than normal

754/2721(27.71)

 

1.12(1.03–1.16)

HDL leveld

 

0.9913

 

 Normal

3420/15246(22.43)

  

 Higher than normal

452/2014(22.44)

  

BMI (kg/m2)

 

0.0028

 

 <18.5

168/908(18.50)

 

0.80(0.66–1.01)

 18.5–24.0

1987/9046(21.97)

 

Reference

 24.0–28.0

1254/5350(23.44)

 

1.07(0.98–1.17)

 ≥28.0

464/1960(23.67)

 

1.15(1.01–1.31)

  1. Abbreviations: BMI = body mass index. BCG = Bacillus Calmette-Guerin. CI = confidence interval. HDL = high density lipoprotein. LDL = low density lipoprotein. OR = odds ratio. QFT = QuantiFERON-TB Gold In-Tube. TB = tuberculosis. T2DM = type 2 diabetes mellitus.
  2. *Controlling for variables with p < 0.05 in the univariate analysis.
  3. a,b,c,dRanges of normal value for blood tests in different study sites: Cholesterol: Site A = 2.59–5.17 mmol/L, Site B = 3.1–5.17 mmol/L, Site C = 0–5.17 mmol/L, Site D = 0–5.17 mmol/L. Triglyceride: Site A = 0–1.7 mmol/L, Site B = 0.56–1.7 mmol/L, Site C = 0–1.71 mmol/L, Site D = 0–2.3 mmol/L. HDL: Site A = >0.9 mmol/L, Site B = 0.9–2.28 mmol/L, Site C = 1.16–1.55 mmol/L, Site D = 1.05–1.74 mmol/L. LDL: Site A = 0–4.11 mmol/L, Site B = 0–3.36 mmol/L, Site C = 0–3.12 mmol/L, Site D = <3.1 mmol/L.