Figure 1: Structure of ANG with ALS/PD variants marked. | Scientific Reports

Figure 1: Structure of ANG with ALS/PD variants marked.

From: Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis

Figure 1

The active site residues (H13, K40, H114) and the nuclear localization sequence (R31, R32, R33) are shown and are labelled in black along with the N- and C-termini. The disulphide bridges are also shown. K40 and R31 both show multiple conformations. Helices are labelled in dark green and strands in pink. Figures were created using the program PyMOL (http://www.delanoscientific.com)

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